Allergen-specific immunotherapy (SIT), also known as therapeutic vaccination, is a clinically effective treatment for allergies. People who have had reactions to the egg with symptoms such as angioedema, difficulty breathing, lightheadedness, or recurrent emesis, or who needed epinephrine or other emergency medical intervention, can receive any authorized inactivated flu vaccine that is appropriate for their age and health status. If a person has severe egg sensitivity or has tested positive for yellow fever vaccine skin tests but needs to be vaccinated due to the risk of the travel destination, desensitization can be done under the direct supervision of a physician experienced in treating anaphylaxis. In such cases, both the yellow fever vaccine and the flu vaccine should be administered in an inpatient or outpatient medical setting.
The administration of the vaccine should be supervised by a healthcare provider who is able to recognize and control serious allergic reactions. A serious allergic reaction prior to any vaccine is a contraindication to receiving the vaccine in the future. Vaccines are designed to activate the immune system and help it become familiar with and protect against potential threats. Mild reactions are common due to this activation of the immune system.
What is the allergologist's role in vaccine reactions? An allergist can determine if it's safe for your child to receive a vaccine if you have a worrying history of allergies to vaccines or excipients, or evaluate your child after having had an allergic reaction to a vaccine. Clinical trials with new vaccines indicate that widespread vaccination against allergies could help control the allergy pandemic. Thanks to the molecular characterization of allergens, new forms of allergy diagnosis and allergy vaccines based on recombinant allergen derivatives, peptides and allergenic genes have emerged. It will be necessary to carry out studies in experimental animal models and on non-allergic people with genetically modified allergenic derivatives and epitopes to develop prophylactic vaccination and tolerance induction strategies in order to prevent allergies, which could ultimately stop the allergy pandemic.
